Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients
Joint Authors
Rosenau, Emma
Salmasinia, Donya
Hsu, Jack
Cline, Christina
Hou, Wei
Moreb, Jan S.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Poor peripheral blood stem cell (PBSC) mobilization predicts worse outcome for myeloma and lymphoma patients post autologous stem cell transplant (ASCT).
We hypothesize that PBSC harvest using plerixafor and G-CSF in poor mobilizers may improve long-term outcome.
We retrospectively analyzed the data on patients who had second PBSC mobilization using plerixafor and G-CSF as a rescue.
Nine lymphoma and 8 multiple myeloma (MM) patients received the drug.
A control group of 25 MM and lymphoma patients who were good mobilizers with G-CSF only was used for comparison.
Sixteen of the 17 poor mobilizers proceeded to ASCT, and one MM patient had tandem transplants.
Length of hospital stay, infection incidence, granulocyte engraftment, and long-term hematopoietic recovery were not significantly different between the two groups.
In conclusion, all poor mobilizers were able to obtain adequate stem cells transplant dose and had similar transplant course and long-term outcome to that of the control good mobilizers group.
American Psychological Association (APA)
Moreb, Jan S.& Salmasinia, Donya& Hsu, Jack& Hou, Wei& Cline, Christina& Rosenau, Emma. 2011. Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients. Advances in Hematology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-477999
Modern Language Association (MLA)
Moreb, Jan S.…[et al.]. Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients. Advances in Hematology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-477999
American Medical Association (AMA)
Moreb, Jan S.& Salmasinia, Donya& Hsu, Jack& Hou, Wei& Cline, Christina& Rosenau, Emma. Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients. Advances in Hematology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-477999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477999