Mediators of Inflammation-Induced Bone Damage in Arthritis and Their Control by Herbal Products
Joint Authors
Moudgil, Kamal D.
Nanjundaiah, Siddaraju M.
Astry, Brian
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-07
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the synovial joints leading to bone and cartilage damage.
Untreated inflammatory arthritis can result in severe deformities and disability.
The use of anti-inflammatory agents and biologics has been the mainstay of treatment of RA.
However, the prolonged use of such agents may lead to severe adverse reactions.
In addition, many of these drugs are quite expensive.
These limitations have necessitated the search for newer therapeutic agents for RA.
Natural plant products offer a promising resource for potential antiarthritic agents.
We describe here the cellular and soluble mediators of inflammation-induced bone damage (osteoimmunology) in arthritis.
We also elaborate upon various herbal products that possess antiarthritic activity, particularly mentioning the specific target molecules.
As the use of natural product supplements by RA patients is increasing, this paper presents timely and useful information about the mechanism of action of promising herbal products that can inhibit the progression of inflammation and bone damage in the course of arthritis.
American Psychological Association (APA)
Nanjundaiah, Siddaraju M.& Astry, Brian& Moudgil, Kamal D.. 2013. Mediators of Inflammation-Induced Bone Damage in Arthritis and Their Control by Herbal Products. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-20.
https://search.emarefa.net/detail/BIM-478046
Modern Language Association (MLA)
Nanjundaiah, Siddaraju M.…[et al.]. Mediators of Inflammation-Induced Bone Damage in Arthritis and Their Control by Herbal Products. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-20.
https://search.emarefa.net/detail/BIM-478046
American Medical Association (AMA)
Nanjundaiah, Siddaraju M.& Astry, Brian& Moudgil, Kamal D.. Mediators of Inflammation-Induced Bone Damage in Arthritis and Their Control by Herbal Products. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-20.
https://search.emarefa.net/detail/BIM-478046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478046