Recent Advances in Chemical Modification of Peptide Nucleic Acids
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology.
Although PNA recognizes single-stranded nucleic acids with exceptionally high affinity and sequence selectivity, there is considerable ongoing effort to further improve properties of PNA for both fundamental science and practical applications.
The present paper discusses selected recent studies that improve on cellular uptake and binding of PNA to double-stranded DNA and RNA.
The focus is on chemical modifications of PNA's backbone and heterocyclic nucleobases.
The paper selects representative recent studies and does not attempt to provide comprehensive coverage of the broad and vibrant field of PNA modification.
American Psychological Association (APA)
Rozners, Eriks. 2012. Recent Advances in Chemical Modification of Peptide Nucleic Acids. Journal of Nucleic Acids،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478049
Modern Language Association (MLA)
Rozners, Eriks. Recent Advances in Chemical Modification of Peptide Nucleic Acids. Journal of Nucleic Acids No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-478049
American Medical Association (AMA)
Rozners, Eriks. Recent Advances in Chemical Modification of Peptide Nucleic Acids. Journal of Nucleic Acids. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478049
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478049