Conjunctivitis and Total IgE in Lacrimal Fluid : Lacrytest Screening
Joint Authors
Cisteró-Bahima, Anna
Torres, Ferran
Bartra, Joan
Monzón, Susana
San Miguel, M. del Mar
Basagaña, María
Arrondo, Elena
Alonso, Rosario
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-04-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Total tear IgE has been considered to play an important role in allergic conjunctivitis, and measurement has been considered useful for diagnosis.
The aim of this study was to ascertain whether Lacrytest®, a new commercialised method to detect IgE levels in lacrimal fluid, could constitute a screening test for the diagnosis of allergic conjunctivitis.
This was a cross-sectional study.
Patients with seasonal and perennial allergic conjunctivitis, vernal keratoconjunctivitis and a control group were included.
Clinical history, ophthalmic examination, skin prick test and conjunctival provocation test were obtained.
Lacrytest® was later performed in all groups.
Fifty-four patients were enrolled: thirty with IgE-mediated conjunctivitis and, nine with vernal keratoconjunctivitis and fifteen controls.
Lacrytest® was negative in all controls, positive in 20% of the IgE-mediated conjunctivitis group and in 88.9% of the vernal keratoconjunctivitis group.
Global statistically-significant differences were found among the three groups (P=.003).
Sensitivity of the test in the IgE-mediated conjunctivitis group was 20%, specificity 100%, positive predictive value 100%, and negative predictive value 38.46%, while in VKC sensitivity was 88.88%, specificity 100%, positive predictive value 100%, and negative predictive value 93.75%.
Our data confirm that this test is not useful for screening allergic conjunctivitis.
Lacrytest®, while not providing any useful information to an allergist, could be helpful for ophthalmologists to confirm an IgE-mediated or VKC conjunctivitis.
American Psychological Association (APA)
Monzón, Susana& Arrondo, Elena& Bartra, Joan& Torres, Ferran& Basagaña, María& San Miguel, M. del Mar…[et al.]. 2009. Conjunctivitis and Total IgE in Lacrimal Fluid : Lacrytest Screening. Journal of Allergy،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-478115
Modern Language Association (MLA)
Monzón, Susana…[et al.]. Conjunctivitis and Total IgE in Lacrimal Fluid : Lacrytest Screening. Journal of Allergy No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-478115
American Medical Association (AMA)
Monzón, Susana& Arrondo, Elena& Bartra, Joan& Torres, Ferran& Basagaña, María& San Miguel, M. del Mar…[et al.]. Conjunctivitis and Total IgE in Lacrimal Fluid : Lacrytest Screening. Journal of Allergy. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-478115
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478115