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A Case of a Metastatic Disease to the Pancreas from a Small-Cell Lung Carcinoma Documented by a CT-Scan-Guided Trucut Biopsy : The Diagnostic Role of Cytomorphology and Immunohistochemistry
Joint Authors
Mellas, Naoufal
Hijri, F. Z.
Arifi, S.
Benhammane, Hafida
Daoudi, K.
Moumna, K.
Bouyahia, N.
Brahmi, S. A.
El Mesbahi, Omar
Amarti, A.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Unlike primary pancreatic carcinoma, metastatic lesions of the pancreas are uncommon and account for approximately 2% of pancreatic malignancies.
Small-cell lung carcinoma (SCLC) represents a group of highly malignant tumors giving rise to early and widespread metastasis at the time of diagnosis.
However, the pancreas is a relatively infrequent site of metastasis by this neoplasm, and reports on metastatic small-cell carcinoma (SCC) in the pancreas, either of pulmonary or extrapulmonary origin, to be diagnosed by CT-scan-guided trucut biopsy (CT-TCB) are very rare.
A 56-year-old man presented with a laterocervical lymphadenopathy associated to a mixed-density lung mass and a mass in the pancreatic body.
CT-TCB slides from the pancreatic mass contained small, round tumor cells with extensive nuclear molding.
The cytomorphological and histological diagnosis was metastatic SCC.
Immunocytochemical staining showed that a variable number of neoplastic cells were positive for cytokeratin 7, TTF1, chromogranin A, and synaptophysin but negative for leukocyte common antigen and cytokeratin 20 with a very high expression of KI67.
The transbronchial needle biopsy confirmed the diagnosis of an SCC.
This case represents a rare metastatic lesion in the pancreas from SCLC, diagnosed by CT-TCB histological and immunohistochemical studies.
American Psychological Association (APA)
Bouyahia, N.& Daoudi, K.& Moumna, K.& Hijri, F. Z.& Benhammane, Hafida& Brahmi, S. A.…[et al.]. 2012. A Case of a Metastatic Disease to the Pancreas from a Small-Cell Lung Carcinoma Documented by a CT-Scan-Guided Trucut Biopsy : The Diagnostic Role of Cytomorphology and Immunohistochemistry. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-478258
Modern Language Association (MLA)
Bouyahia, N.…[et al.]. A Case of a Metastatic Disease to the Pancreas from a Small-Cell Lung Carcinoma Documented by a CT-Scan-Guided Trucut Biopsy : The Diagnostic Role of Cytomorphology and Immunohistochemistry. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-478258
American Medical Association (AMA)
Bouyahia, N.& Daoudi, K.& Moumna, K.& Hijri, F. Z.& Benhammane, Hafida& Brahmi, S. A.…[et al.]. A Case of a Metastatic Disease to the Pancreas from a Small-Cell Lung Carcinoma Documented by a CT-Scan-Guided Trucut Biopsy : The Diagnostic Role of Cytomorphology and Immunohistochemistry. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-478258
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478258