Myeloid Sarcoma : Clinicopathologic, Cytogenetic, and Outcome Analysis of 21 Adult Patients
Joint Authors
Marei, Lina
Abbasi, Salah
Haddad, Husam
Badheeb, Ahmed
al-Khateeb, Hani
Source
Leukemia Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Mechanical Engineering
Medicine
Abstract EN
Myeloid sarcoma (MS) is a neoplasm of immature granulocytes, monocytes, or both involving any extramedullary site.
Twenty one patients with MS at diagnosis who were treated at King Hussein Cancer Center in Jordan were included in this retrospective study with a male to female ratio of 2 : 1.
The most common site was the reticuloendothelial system.
The most common morphology subtype was M2 (38%) and the most frequent chromosomal abnormality was trisomy 8.
Twenty patients received induction chemotherapy; only 14 (70%) achieved complete remission.
Median survival time was 24.7 months for the whole group and 58.6 months for patients who underwent allogenic bone marrow transplant.
This paper showed that MS has frequent M2 morphology, carries chromosomal aberrations other than t(8;21), and requires aggressive therapy as a front line approach.
American Psychological Association (APA)
al-Khateeb, Hani& Badheeb, Ahmed& Haddad, Husam& Marei, Lina& Abbasi, Salah. 2010. Myeloid Sarcoma : Clinicopathologic, Cytogenetic, and Outcome Analysis of 21 Adult Patients. Leukemia Research and Treatment،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-478413
Modern Language Association (MLA)
al-Khateeb, Hani…[et al.]. Myeloid Sarcoma : Clinicopathologic, Cytogenetic, and Outcome Analysis of 21 Adult Patients. Leukemia Research and Treatment No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-478413
American Medical Association (AMA)
al-Khateeb, Hani& Badheeb, Ahmed& Haddad, Husam& Marei, Lina& Abbasi, Salah. Myeloid Sarcoma : Clinicopathologic, Cytogenetic, and Outcome Analysis of 21 Adult Patients. Leukemia Research and Treatment. 2010. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-478413
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478413