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Metronidazole-Induced Pancreatitis
Joint Authors
O'Halloran, E.
Hogan, A.
Mealy, K.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Case Summary.
A 25-year-old caucasian lady presented to the Accident & Emergency department complaining of acute onset severe epigastric pain radiating through to the back with associated nausea and vomiting.
A diagnosis of acute pancreatitis was made.
Symptoms commenced after the third dose of Metronidazole therapy prescribed for a recurrent periodontal abscess.
The patient described a similar episode 10 months previously.
On neither occasion were any other medications being taken, there was no history of alcohol abuse and no other gastro-intestinal aetiology could be identified on imaging.
Symptoms resolved quickly upon discontinuation of the antibiotic agent.
We conclude therefore that Metronidazole can reasonably be identified as the only potential causative agent.
Discussion.
The proportion of cases of pancreatitis caused by drugs is estimated to be around 2% in the general population.
The exact mechanism of action of Metronidazole induced pancreatitis is unclear but a trigger role for the drug seems likely.
Conclusion.
This case provides the eighth report of Metronidazole induced pancreatitis.
All of the cases were reported in females and ran a benign course.Early diagnosis, discontinuation of the drug and supportive care will lead to a successful recovery in the majority of cases.
American Psychological Association (APA)
O'Halloran, E.& Hogan, A.& Mealy, K.. 2010. Metronidazole-Induced Pancreatitis. HPB Surgery،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-478428
Modern Language Association (MLA)
O'Halloran, E.…[et al.]. Metronidazole-Induced Pancreatitis. HPB Surgery No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-478428
American Medical Association (AMA)
O'Halloran, E.& Hogan, A.& Mealy, K.. Metronidazole-Induced Pancreatitis. HPB Surgery. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-478428
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478428