A Comparison Study of the Blood Component Quality of Whole Blood Held Overnight at 4°C or Room Temperature
Joint Authors
Li, Ruiqing
Fan, Yahan
Yi, Zhongmei
Wang, Shichun
Huang, Shan
Wang, Tiantian
Zhao, Shuming
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The use of plasma frozen within 24 hrs is likely to increase.
Whole blood (WB) and buffy coats (BCs) can be held for a few hrs or overnight before processing.
Methods.
Twenty-four bags of WB for plasma and 12 bags for platelet (PLT) concentrates were collected.
The fresh frozen plasma (FFP) was prepared within 6 hrs.
I-FP24 and II-FP24 samples were prepared either from leukodepleted WB that was held overnight or from WB that was held overnight before leukodepletion.
The PLT concentrates (PCs) were prepared from BCs within 6 hrs (PC1) and within 18 to 24 hrs (PC2).
The typical coagulation factors and some biochemical parameters were determined.
Results.
Compared to the FFP samples, the levels of FVII and FVIII in the I-FP24 and II-FP24 samples decreased significantly.
The pH, Na+, LDH, and FHb levels differed significantly between II-FP24 and FFP.
Compared to PC1, PC2 exhibited lower pH, pO2, and Na+ levels, a higher PLT count, and increased pCO2, K+, Lac, and CD62P expression levels.
Conclusion.
FP24 is best prepared from WB that was stored overnight at 4°C and then leukodepleted and separated within 24 hrs.
PCs are best produced from BCs derived from WB that was held overnight at room temperature.
American Psychological Association (APA)
Wang, Shichun& Wang, Tiantian& Fan, Yahan& Huang, Shan& Yi, Zhongmei& Li, Ruiqing…[et al.]. 2013. A Comparison Study of the Blood Component Quality of Whole Blood Held Overnight at 4°C or Room Temperature. Journal of Blood Transfusion،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-478435
Modern Language Association (MLA)
Wang, Shichun…[et al.]. A Comparison Study of the Blood Component Quality of Whole Blood Held Overnight at 4°C or Room Temperature. Journal of Blood Transfusion No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-478435
American Medical Association (AMA)
Wang, Shichun& Wang, Tiantian& Fan, Yahan& Huang, Shan& Yi, Zhongmei& Li, Ruiqing…[et al.]. A Comparison Study of the Blood Component Quality of Whole Blood Held Overnight at 4°C or Room Temperature. Journal of Blood Transfusion. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-478435
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478435