Hierarchical Modular Structure Identification with Its Applications in Gene Coexpression Networks
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Network module (community) structure has been a hot research topic in recent years.
Many methods have been proposed for module detection and identification.
Hierarchical structure of modules is shown to exist in many networks such as biological networks and social networks.
Compared to the partitional module identification methods, less research is done on the inference of hierarchical modular structure.
In this paper, we propose a method for constructing the hierarchical modular structure based on the stochastic block model.
Statistical tests are applied to test the hierarchical relations between different modules.
We give both artificial networks and real data examples to illustrate the performance of our approach.
Application of the proposed method to yeast gene coexpression network shows that it does have a hierarchical modular structure with the modules on different levels corresponding to different gene functions.
American Psychological Association (APA)
Zhang, Shuqin. 2012. Hierarchical Modular Structure Identification with Its Applications in Gene Coexpression Networks. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478455
Modern Language Association (MLA)
Zhang, Shuqin. Hierarchical Modular Structure Identification with Its Applications in Gene Coexpression Networks. The Scientific World Journal No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-478455
American Medical Association (AMA)
Zhang, Shuqin. Hierarchical Modular Structure Identification with Its Applications in Gene Coexpression Networks. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478455