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Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-30
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
In the course of evolution, viruses have developed various molecular mechanisms to evade the defense reactions of the host organism.
When understanding the mechanisms used by viruses to overcome manifold defense systems of the animal organism, represented by molecular factors and cells of the immune system, we would not only comprehend better but also discover new patterns of organization and function of these most important reactions directed against infectious agents.
Here, study of the orthopoxviruses pathogenic for humans, such as variola (smallpox), monkeypox, cowpox, and vaccinia viruses, may be most important.
Analysis of the experimental data, presented in this paper, allows to infer that variola virus and other orthopoxviruses possess an unexampled set of genes whose protein products efficiently modulate the manifold defense mechanisms of the host organisms compared with the viruses from other families.
American Psychological Association (APA)
Shchelkunov, Sergei N.. 2012. Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism. Advances in Virology،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-478568
Modern Language Association (MLA)
Shchelkunov, Sergei N.. Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism. Advances in Virology No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-478568
American Medical Association (AMA)
Shchelkunov, Sergei N.. Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism. Advances in Virology. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-478568
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478568