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Ret Finger Protein : An E3 Ubiquitin Ligase Juxtaposed to the XY Body in Meiosis
Joint Authors
Gillot, Isabelle
Matthews, Cédric
Lopez, Pascal
Puel, Daniel
Vidal, Frédérique
Source
International Journal of Cell Biology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
During prophase I of male meiosis, the sex chromosomes form a compact structure called XY body that associates with the nuclear membrane of pachytene spermatocytes.
Ret Finger Protein is a transcriptional repressor, able to interact with both nuclear matrix-associated proteins and double-stranded DNA.
We report the precise and unique localization of Ret Finger Protein in pachytene spermatocytes, in which Ret Finger Protein takes place of lamin B1, between the XY body and the inner nuclear membrane.
This localization of Ret Finger Protein does not seem to be associated with O-glycosylation or sumoylation.
In addition, we demonstrate that Ret Finger Protein contains an E3 ubiquitin ligase activity.
These observations lead to an attractive hypothesis in which Ret Finger Protein would be involved in the positioning and the attachment of XY body to the nuclear lamina of pachytene spermatocytes.
American Psychological Association (APA)
Gillot, Isabelle& Matthews, Cédric& Puel, Daniel& Vidal, Frédérique& Lopez, Pascal. 2010. Ret Finger Protein : An E3 Ubiquitin Ligase Juxtaposed to the XY Body in Meiosis. International Journal of Cell Biology،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-478579
Modern Language Association (MLA)
Gillot, Isabelle…[et al.]. Ret Finger Protein : An E3 Ubiquitin Ligase Juxtaposed to the XY Body in Meiosis. International Journal of Cell Biology No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-478579
American Medical Association (AMA)
Gillot, Isabelle& Matthews, Cédric& Puel, Daniel& Vidal, Frédérique& Lopez, Pascal. Ret Finger Protein : An E3 Ubiquitin Ligase Juxtaposed to the XY Body in Meiosis. International Journal of Cell Biology. 2010. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-478579
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478579