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Microradiography of Microcalcifications in Breast Specimen : A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity
Joint Authors
Jagusch, N.
Langen, H.-J.
Müller, J.
Bielmeier, J.
Wetzler, Th.
Koehler, S.
Jocher, R.
Kranzfelder, D.
Treutlein, G.
Ott, G.
Source
Radiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-11
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Introduction.
Does high-resolution visualization of microcalcifications improve diagnostic reliability? Method.
X-rays were taken of mamma specimens with microcalcifications in 32 patients (10 malignant; 22 benign) using conventional radiography (12 Lp/mm) and high-resolution radiography (2000 Lp/mm).
Histological sections were subsequently prepared and correlated to the microradiographic image and every calcification was assigned an exact malignant or benign histological diagnosis.
Five radiologists classified single groups of calcifications in both methods according to the BIRADS classification system.
Results.
Using microradiography microcalcifications can be shown in high resolution at the cell level including histological correlation.
In some cases, the diagnostic validity was improved by the high resolution in microradiography.
In other cases, the high resolution resulted in more visible calcifications, thus giving benign calcifications a malignant appearance.
In the BIRADS 2 and 3 group, the probability of malignancy was 28.6% in the conventional radiography evaluation and 37.8% in the microradiography evaluation.
In the BIRADS 4 and 5 group, the probability of malignancy was 34.2% in the conventional radiography evaluation and 24.4% in the microradiography evaluation.
The differences were not significant.
Summary.
Overall, the improved resolution in microradiography did not show an improvement in diagnostic accuracy compared to conventional radiography.
American Psychological Association (APA)
Langen, H.-J.& Koehler, S.& Bielmeier, J.& Jocher, R.& Kranzfelder, D.& Jagusch, N.…[et al.]. 2012. Microradiography of Microcalcifications in Breast Specimen : A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity. Radiology Research and Practice،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-478696
Modern Language Association (MLA)
Langen, H.-J.…[et al.]. Microradiography of Microcalcifications in Breast Specimen : A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity. Radiology Research and Practice No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-478696
American Medical Association (AMA)
Langen, H.-J.& Koehler, S.& Bielmeier, J.& Jocher, R.& Kranzfelder, D.& Jagusch, N.…[et al.]. Microradiography of Microcalcifications in Breast Specimen : A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity. Radiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-478696
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478696