Factors Associated with Spontaneous Clearance of Hepatitis C Virus in Chinese Population
Joint Authors
Sun, Haibo
Kong, Fei
Minuk, Gerald Y.
Jin, Jinglan
Sun, Bing
Wu, Ruihong
Lv, Juan
Jiang, Jing
Jia, Jing
Li, Hua
Huang, Xinxing
Yu, Ge
Bai, Yang
Pan, Yu
Ma, Zhenhua
Chen, Linjiao
Zhong, Jin
Wang, Yang
Wang, Xiaomei
Niu, Junqi
Chi, Xiumei
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Hepatitis C virus (HCV) infections spontaneously clear in approximately 15–45% of infected individuals.
Factors which influence spontaneous HCV clearance remain to be identified.
The purpose of the present study was to identify variables associated with spontaneous HCV clearance in a referred population of Chinese patients.
The prevalence of host, viral, and environmental factors known to influence the outcome of HCV infections was compared in 92 HCV spontaneous clearance subjects and 318 HCV persistent infection subjects.
Univariate and multivariate analyses were performed to identify those factors associated with spontaneous HCV clearance.
In univariate analysis, female gender, a history of icteric hepatitis, serologic evidence of concurrent HBV infection, and rs12979860 CC genotype were positively associated with spontaneous HCV clearance, while alcohol consumption was negatively associated with clearance.
In multivariate analysis, female gender, a history of icteric hepatitis, concurrent HBV infection, and rs12979860 CC genotype remained independent variables associated with spontaneous HCV clearance.
Spontaneous HCV clearance is more likely to occur in females, subjects with a history of icteric hepatitis, HBV coinfections, and those with the rs12979860 CC genotype.
American Psychological Association (APA)
Kong, Fei& Pan, Yu& Chi, Xiumei& Wang, Xiaomei& Chen, Linjiao& Lv, Juan…[et al.]. 2014. Factors Associated with Spontaneous Clearance of Hepatitis C Virus in Chinese Population. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-478747
Modern Language Association (MLA)
Kong, Fei…[et al.]. Factors Associated with Spontaneous Clearance of Hepatitis C Virus in Chinese Population. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-478747
American Medical Association (AMA)
Kong, Fei& Pan, Yu& Chi, Xiumei& Wang, Xiaomei& Chen, Linjiao& Lv, Juan…[et al.]. Factors Associated with Spontaneous Clearance of Hepatitis C Virus in Chinese Population. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-478747
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478747