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Multimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient : A Case Report and Literature Review
Joint Authors
Richiusa, Pierina
Lo Casto, Antonio
Guadagnino, Giuliana
Pirrello, Roberto
Moschella, Francesco
Cabibi, Daniela
Di Carlo, Paola
Sarno, Caterina
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetes is a well-known risk factor for invasive mucormycosis with rhinocerebral involvement.
Acute necrosis of the maxilla is seldom seen and extensive facial bone involvement is rare in patients with rhino-orbital-cerebral mucormycosis.
An aggressive surgical approach combined with antifungal therapy is usually necessary.
In this report, we describe the successful, personalized medical and surgical management of extensive periorbital mucormycosis in an elderly diabetic, HIV-negative woman.
Mono- or combination therapy with liposomal amphotericin B (L-AmB) and posaconazole (PSO) and withheld debridement is discussed.
The role of aesthetic plastic surgery to preserve the patient’s physical appearance is also reported.
Any diabetic patient with sinonasal disease, regardless of their degree of metabolic control, is a candidate for prompt evaluation to rule out mucormycosis.
Therapeutic and surgical strategies and adjunctive treatments are essential for successful disease management.
These interventions may include combination therapy.
Finally, a judicious multimodal treatment approach can improve appearance and optimize outcome in elderly patients.
American Psychological Association (APA)
Di Carlo, Paola& Pirrello, Roberto& Guadagnino, Giuliana& Richiusa, Pierina& Lo Casto, Antonio& Sarno, Caterina…[et al.]. 2014. Multimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient : A Case Report and Literature Review. Case Reports in Medicine،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-478753
Modern Language Association (MLA)
Di Carlo, Paola…[et al.]. Multimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient : A Case Report and Literature Review. Case Reports in Medicine No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-478753
American Medical Association (AMA)
Di Carlo, Paola& Pirrello, Roberto& Guadagnino, Giuliana& Richiusa, Pierina& Lo Casto, Antonio& Sarno, Caterina…[et al.]. Multimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient : A Case Report and Literature Review. Case Reports in Medicine. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-478753
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478753