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Challenges in Diagnosis and Treatment of a Cervical Spinal Cord Injury Patient with Melanoma, Adenocarcinoma, and Hepatic and Osteolytic Metastases : Need to Implement Strategies for Prevention and Early Detection of Cancer in Spinal Cord Injury Patients
Joint Authors
Mansour, Paul
Vaidyanathan, Subramanian
Selmi, Fahed
Soni, Bakul M.
Hughes, Peter L.
Singh, Gurpreet
Pulya, Kamesh
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A male tetraplegic patient with, who had been taking warfarin, developed haematuria.
Ultrasound scan revealed no masses, stones, or hydronephrosis.
Urinary bladder had normal configuration with no evidence of masses or organised haematoma.
Urine cytology revealed no malignant cells.
Four months later, CT urography revealed an irregular mass at the base of urinary bladder.
Cystoscopic biopsy revealed moderately differentiated adenocarcinoma, which contained goblet cells and pools of mucin showing strongly positive immunostaining for prostatic acid hosphatase and patchy staining for prostate specific antigen.
Computed Tomography revealed multiple hypodense hepatic lesions and several osteolytic areas in femoral heads and iliac bone.
With a presumptive diagnosis of prostatic carcinoma, leuprorelin acetate 3.75 mg was prescribed.
This patient expired a month later.
Conclusion.
(i) Spinal cord injury patient, who passed blood in urine while taking warfarin, requires repeated investigations to look for urinary tract neoplasm.
(ii) Anti-androgen therapy should be prescribed for 2 weeks prior to administration of gonadorelin analogue to prevent tumour flare causing bone pain, bladder outlet obstruction, uraemia, and cardiovascular risk due to hypercoagulability associated with a rapid increase in tumour burden.
(iii) Spinal cord physicians should adopt a caring and compassionate approach while managing tetraplegic patients with several co-morbidities, as aggressive diagnostic tests and therapeutic procedures may lead to deterioration in the quality of life.
American Psychological Association (APA)
Vaidyanathan, Subramanian& Mansour, Paul& Hughes, Peter L.& Selmi, Fahed& Singh, Gurpreet& Pulya, Kamesh…[et al.]. 2012. Challenges in Diagnosis and Treatment of a Cervical Spinal Cord Injury Patient with Melanoma, Adenocarcinoma, and Hepatic and Osteolytic Metastases : Need to Implement Strategies for Prevention and Early Detection of Cancer in Spinal Cord Injury Patients. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-479150
Modern Language Association (MLA)
Vaidyanathan, Subramanian…[et al.]. Challenges in Diagnosis and Treatment of a Cervical Spinal Cord Injury Patient with Melanoma, Adenocarcinoma, and Hepatic and Osteolytic Metastases : Need to Implement Strategies for Prevention and Early Detection of Cancer in Spinal Cord Injury Patients. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-479150
American Medical Association (AMA)
Vaidyanathan, Subramanian& Mansour, Paul& Hughes, Peter L.& Selmi, Fahed& Singh, Gurpreet& Pulya, Kamesh…[et al.]. Challenges in Diagnosis and Treatment of a Cervical Spinal Cord Injury Patient with Melanoma, Adenocarcinoma, and Hepatic and Osteolytic Metastases : Need to Implement Strategies for Prevention and Early Detection of Cancer in Spinal Cord Injury Patients. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-479150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479150