Bimodal Fluorescence and Magnetic Resonance Imaging Using Water-Soluble Hexagonal NaYF4 : Ce,Tb,Gd Nanocrystals
Joint Authors
Ren, Wen Ting
Wu, Qi Zhu
Qi, Fei
Yu, Xue Feng
Liang, Liang Bo
Huang, Xiao Qi
Gong, Qi Yong
Quan, Hong
Zhu, Hong Yan
Yang, Zhi Yong
Sun, Zheng Bo
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The present study explored the feasibility of using hexagonal-phase NaYF4:Ce,Tb,Gd nanocrystals as bimodal probes for fluorescence and magnetic resonance (MR) imaging.
Using a facile and user-friendly strategy, the NaYF4:Ce,Tb,Gd nanocrystals were synthesized with good water dispensability, high quantum yield (26%), and decent MR T1 relaxivity (r1=2.87 mM−1 s−1).
The NaYF4:Ce,Tb,Gd NCs conjugated by folic acid presented great efficiency in fluorescence imaging of C6 glioma cells in vitro.
Meanwhile, in in vivo MR experiments on rats, the NaYF4:Ce,Tb,Gd NCs also significantly increased T1 signal in the liver, spleen, and kidney even with a low probe dose.
The proposed NaYF4:Ce,Tb,Gd nanoprobes hold promise for simultaneous bimodal fluorescence and MR bioimaging.
American Psychological Association (APA)
Ren, Wen Ting& Liang, Liang Bo& Qi, Fei& Sun, Zheng Bo& Yang, Zhi Yong& Huang, Xiao Qi…[et al.]. 2011. Bimodal Fluorescence and Magnetic Resonance Imaging Using Water-Soluble Hexagonal NaYF4 : Ce,Tb,Gd Nanocrystals. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-479151
Modern Language Association (MLA)
Ren, Wen Ting…[et al.]. Bimodal Fluorescence and Magnetic Resonance Imaging Using Water-Soluble Hexagonal NaYF4 : Ce,Tb,Gd Nanocrystals. Journal of Nanomaterials No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-479151
American Medical Association (AMA)
Ren, Wen Ting& Liang, Liang Bo& Qi, Fei& Sun, Zheng Bo& Yang, Zhi Yong& Huang, Xiao Qi…[et al.]. Bimodal Fluorescence and Magnetic Resonance Imaging Using Water-Soluble Hexagonal NaYF4 : Ce,Tb,Gd Nanocrystals. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-479151
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479151
