Legume Lectin FRIL Preserves Neural Progenitor Cells in Suspension Culture In Vitro
Joint Authors
Li, Yanhua
Nan, Xue
Yao, Hailei
Pei, Xuetao
Wang, Dongmei
Wang, Yunfang
Xie, Xiaoyan
Shi, Shuangshuang
Bai, Cixian
Han, Shu
Source
Clinical and Developmental Immunology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-08-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
In vitro maintenance of stem cells is crucial for many clinical applications.
Stem cell preservation factor FRIL (Flt3 receptor-interacting lectin) is a plant lectin extracted from Dolichos Lablab and has been found preserve hematopoietic stem cells in vitro for a month in our previous studies.
To investigate whether FRIL can preserve neural progenitor cells (NPCs), it was supplemented into serum-free suspension culture media.
FRIL made NPC grow slowly, induced cell adhesion, and delayed neurospheres formation.
However, FRIL did not initiate NPC differentiation according to immunofluorescence and semiquantitive RT-PCR results.
In conclusion, FRIL could also preserve neural progenitor cells in vitro by inhibiting both cell proliferation and differentiation.
American Psychological Association (APA)
Yao, Hailei& Xie, Xiaoyan& Li, Yanhua& Wang, Dongmei& Han, Shu& Shi, Shuangshuang…[et al.]. 2008. Legume Lectin FRIL Preserves Neural Progenitor Cells in Suspension Culture In Vitro. Clinical and Developmental Immunology،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-479158
Modern Language Association (MLA)
Yao, Hailei…[et al.]. Legume Lectin FRIL Preserves Neural Progenitor Cells in Suspension Culture In Vitro. Clinical and Developmental Immunology No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-479158
American Medical Association (AMA)
Yao, Hailei& Xie, Xiaoyan& Li, Yanhua& Wang, Dongmei& Han, Shu& Shi, Shuangshuang…[et al.]. Legume Lectin FRIL Preserves Neural Progenitor Cells in Suspension Culture In Vitro. Clinical and Developmental Immunology. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-479158
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479158