Brugada Syndrome and Pregnancy : Highlights on Antenatal and Prenatal Management
Joint Authors
Alio, Luigi
Maiorana, Antonio
Giambanco, Laura
Alio, Walter
Incandela, Domenico
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-22
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Introduction.
Brugada syndrome is characterized by a disruption of heart’s normal rhythm.
It is an autosomal dominant disease due to a mutation of SNC5A gene.
Its prevalence is low all over the world, but it is a lethal disease.
Sudden cardiac death is the result of phenotypic manifestation of Brugada syndrome.
Among asymptomatic Brugada patients, arrhythmia could be provoked by physical activity, fever, or pregnancy.
About obstetrical management, very few data or reports have been published since this syndrome has been diagnosed in late 1992.
Case Presentation.
A 20-year-old pregnant woman at 13 weeks of gestation was referred to our department because of her familial history of sudden cardiac deaths.
Brothers and sisters of her mother died of Brugada syndrome in childhood or older and live components of this family were carrier of mutation in Brugada gene.
The pregnancy was uneventful.
The patient gave birth vaginally without any arrhythmia.
Strictly cardiological monitoring was performed during labour, delivery, and 12 hours of the postpartum.
Conclusion.
Even though patient at low risk may never have arrhythmia, some conditions could represent a Brugada trigger.
The management could be very easy and uneventful.
Otherwise it could be very difficult with need of ECMO or antiarrhythmics drugs or intracardiac device.
Obstetrical management of Brugada pregnant women should be very strict and multidisciplinary in cooperation with cardiologist and anaesthesiologist and should provide an informed consent to the couple.
American Psychological Association (APA)
Giambanco, Laura& Incandela, Domenico& Maiorana, Antonio& Alio, Walter& Alio, Luigi. 2014. Brugada Syndrome and Pregnancy : Highlights on Antenatal and Prenatal Management. Case Reports in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-479185
Modern Language Association (MLA)
Giambanco, Laura…[et al.]. Brugada Syndrome and Pregnancy : Highlights on Antenatal and Prenatal Management. Case Reports in Obstetrics and Gynecology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-479185
American Medical Association (AMA)
Giambanco, Laura& Incandela, Domenico& Maiorana, Antonio& Alio, Walter& Alio, Luigi. Brugada Syndrome and Pregnancy : Highlights on Antenatal and Prenatal Management. Case Reports in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-479185
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479185