Rapid Progression of a Urinary Bladder Leiomyosarcoma : Report of a Case

Abstract EN

The case we report shows rapid progression and a very poor prognosis only for a month that differs from the clinical course reported in the literature.

An 83-year-old man was referred to our hospital for macroscopic hematuria.

Computed tomography (CT) revealed a large bladder tumor measuring 4 cm × 3 cm and magnetic resonance imaging revealed extravesical invasion and pelvic wall invasion of the tumors.

Chest CT and bone scintigraphy revealed no evidence of distant visceral metastases, and a clinical diagnosis of T4N0M0 was made.

Transurethral resection of the bladder tumor (TUR-BT) was performed for histopathological diagnosis 18 days after admission, and no further adjuvant treatment was given.

At 15 days after TUR-BT, the patient's clinical status worsened with symptoms of exertional dyspnea.

CT showed multiple metastatic lesions in the lung, liver, and retroperitoneal lymphadenopathy.

The patient died 2 days later and underwent autopsy.

A final histopathological diagnosis of leiomyosarcoma was made based on immunohistochemical staining.