The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma
Joint Authors
Sartori, Alessandro
Lo Mele, Luigi
Pranno, Nicola
Barchetti, Giovanni
Gigli, Silvia
Barchetti, Flavio
Giraldi, Guglielmo
Marsella, Luigi Tonino
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
The aim of this study was to validate the role of diffusion-weighted imaging (DWI) at 3 Tesla in the differential diagnosis between benign and malignant laterocervical lymph nodes in patients with head and neck squamous cell carcinoma (HNSCC).
Materials and Methods.
Before undergoing surgery, 80 patients, with biopsy proven HNSCC, underwent a magnetic resonance exam.
Sensitivity (Se) and specificity (Spe) of conventional criteria and DWI in detecting laterocervical lymph node metastases were calculated.
Histological results from neck dissection were used as standard of reference.
Results.
In the 239 histologically proven metastatic lymphadenopathies, the mean apparent diffusion coefficient (ADC) value was 0.903 × 10−3 mm2/sec.
In the 412 pathologically confirmed benign lymph nodes, an average ADC value of 1.650 × 10−3 mm2/sec was found.
For differentiating between benign versus metastatic lymph nodes, DWI showed Se of 97% and Spe of 93%, whereas morphological criteria displayed Se of 61% and Spe of 98%.
DWI showed an area under the ROC curve (AUC) of 0.964, while morphological criteria displayed an AUC of 0.715.
Conclusions.
In a DWI negative neck for malignant lymph nodes, the planned dissection could be converted to a wait-and-scan policy, whereas DWI positive neck would support the decision to perform a neck dissection.
American Psychological Association (APA)
Barchetti, Flavio& Pranno, Nicola& Giraldi, Guglielmo& Sartori, Alessandro& Gigli, Silvia& Barchetti, Giovanni…[et al.]. 2014. The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-479227
Modern Language Association (MLA)
Barchetti, Flavio…[et al.]. The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-479227
American Medical Association (AMA)
Barchetti, Flavio& Pranno, Nicola& Giraldi, Guglielmo& Sartori, Alessandro& Gigli, Silvia& Barchetti, Giovanni…[et al.]. The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-479227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479227