The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels
Joint Authors
Ingram, J.
Adams, J. B.
El-Dahr, J. M.
Bradstreet, J.
Baral, M.
Rubin, R. A.
Mitchell, K.
Geis, E.
Zappia, I.
Mitchell, J.
Hensley, A.
Newmark, S.
Gehn, E.
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Pharmacy, Health & Medical Sciences
Medicine
Abstract EN
This study investigated the relationship of children's autism symptoms with their toxic metal body burden and red blood cell (RBC) glutathione levels.
In children ages 3–8 years, the severity of autism was assessed using four tools: ADOS, PDD-BI, ATEC, and SAS.
Toxic metal body burden was assessed by measuring urinary excretion of toxic metals, both before and after oral dimercaptosuccinic acid (DMSA).
Multiple positive correlations were found between the severity of autism and the urinary excretion of toxic metals.
Variations in the severity of autism measurements could be explained, in part, by regression analyses of urinary excretion of toxic metals before and after DMSA and the level of RBC glutathione (adjusted R2 of 0.22–0.45, P<.005 in all cases).
This study demonstrates a significant positive association between the severity of autism and the relative body burden of toxic metals.
American Psychological Association (APA)
Adams, J. B.& Baral, M.& Geis, E.& Mitchell, J.& Ingram, J.& Hensley, A.…[et al.]. 2009. The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels. Journal of Toxicology،Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-479281
Modern Language Association (MLA)
Adams, J. B.…[et al.]. The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels. Journal of Toxicology No. 2009 (2009), pp.1-7.
https://search.emarefa.net/detail/BIM-479281
American Medical Association (AMA)
Adams, J. B.& Baral, M.& Geis, E.& Mitchell, J.& Ingram, J.& Hensley, A.…[et al.]. The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels. Journal of Toxicology. 2009. Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-479281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479281
