Proteins with RNA Chaperone Activity : A World of Diverse Proteins with a Common Task—Impediment of RNA Misfolding
Author
Source
Biochemistry Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-26
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Proteins with RNA chaperone activity are ubiquitous proteins that play important roles in cellular mechanisms.
They prevent RNA from misfolding by loosening misfolded structures without ATP consumption.
RNA chaperone activity is studied in vitro and in vivo using oligonucleotide- or ribozyme-based assays.
Due to their functional as well as structural diversity, a common chaperoning mechanism or universal motif has not yet been identified.
A growing database of proteins with RNA chaperone activity has been established based on evaluation of chaperone activity via the described assays.
Although the exact mechanism is not yet understood, it is more and more believed that disordered regions within proteins play an important role.
This possible mechanism and which proteins were found to possess RNA chaperone activity are discussed here.
American Psychological Association (APA)
Semrad, Katharina. 2010. Proteins with RNA Chaperone Activity : A World of Diverse Proteins with a Common Task—Impediment of RNA Misfolding. Biochemistry Research International،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-479303
Modern Language Association (MLA)
Semrad, Katharina. Proteins with RNA Chaperone Activity : A World of Diverse Proteins with a Common Task—Impediment of RNA Misfolding. Biochemistry Research International No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-479303
American Medical Association (AMA)
Semrad, Katharina. Proteins with RNA Chaperone Activity : A World of Diverse Proteins with a Common Task—Impediment of RNA Misfolding. Biochemistry Research International. 2010. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-479303
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479303