Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi
Joint Authors
Haruna, Emmanuel
Dakare, Monday A.
Ladan, Zakari
Bello, Isaac Asusheyi
Atolagbe, Taofiq O.
Agbaji, Abel S.
Habila, Nathan
Source
Journal of Parasitology Research
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Essential oils (EOs) from Cymbopogon citratus (CC), Eucalyptus citriodora (EC), Eucalyptus camaldulensis (ED), and Citrus sinensis (CS) were obtained by hydrodistillation process.
The EOs were evaluated in vitro for activity against Trypanosoma brucei brucei (Tbb) and Trypanosoma evansi (T.
evansi).
The EOs were found to possess antitrypanosomal activity in vitro in a dose-dependent pattern in a short period of time.
The drop in number of parasite over time was achieved doses of 0.4 g/ml, 0.2 g/mL, and 0.1 g/mL for all the EOs.
The concentration of 0.4 g/mL CC was more potent at 3 minutes and 2 minutes for Tbb and T.
evansi, respectively.
The GC-MS analysis of the EOs revealed presence of Cyclobutane (96.09%) in CS, 6-octenal (77.11%) in EC, Eucalyptol (75%) in ED, and Citral (38.32%) in CC among several other organic compounds.
The results are discussed in relation to trypanosome chemotherapy.
American Psychological Association (APA)
Habila, Nathan& Agbaji, Abel S.& Ladan, Zakari& Bello, Isaac Asusheyi& Haruna, Emmanuel& Dakare, Monday A.…[et al.]. 2010. Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi. Journal of Parasitology Research،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-479375
Modern Language Association (MLA)
Habila, Nathan…[et al.]. Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi. Journal of Parasitology Research No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-479375
American Medical Association (AMA)
Habila, Nathan& Agbaji, Abel S.& Ladan, Zakari& Bello, Isaac Asusheyi& Haruna, Emmanuel& Dakare, Monday A.…[et al.]. Evaluation of In Vitro Activity of Essential Oils against Trypanosoma brucei brucei and Trypanosoma evansi. Journal of Parasitology Research. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-479375
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479375