“Intensity-Response” Effects of Electroacupuncture on Gastric Motility and Its Underlying Peripheral Neural Mechanism
Joint Authors
Xin, Juan-Juan
Wang, Chi
Wang, Xiao-Yu
Shi, Hong
Jing, Xiang-Hong
Zhao, Yu-Feng
Su, Yang-Shuai
He, Wei
Shang, Hong-Yan
Zhu, Bing
Hu, Ling
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aim of this study was to explore the “intensity-response” relationship between EAS and the effect of gastric motility of rats and its underlying peripheral neural mechanism by employing ASIC3 knockout (ASIC3−/−), TRPV1 knockout (TRPV1−/−), and C57BL/6 mice.
For adult male Sprague-Dawley (n=18) rats, the intensities of EAS were 0.5, 1, 3, 5, 7, and 9 mA, respectively.
For mice (n=8 in each group), only 1 mA was used, by which C fiber of the mice can be activated.
Gastric antrum motility was measured by intrapyloric balloon.
Gastric motility was facilitated by EAS at ST36 and inhibited by EAS at CV12.
The half maximal facilitation intensity of EAS at ST36 was 2.1–2.3 mA, and the half maximal inhibitory intensity of EAS at CV12 was 2.8 mA.
In comparison with C57BL/6 mice, the facilitatory effect of ST36 and inhibitive effect of CV12 in ASIC3−/− mice decreased, but the difference was not statistically significant (P>0.05).
However, these effects in TRPV1−/− mice decreased significantly (P<0.001).
The results indicated that there existed an “intensity-response” relationship between EAS and the effect of gastric motility.
TRPV1 receptor was involved in the regulation of gastric motility of EAS.
American Psychological Association (APA)
Su, Yang-Shuai& He, Wei& Wang, Chi& Shi, Hong& Zhao, Yu-Feng& Xin, Juan-Juan…[et al.]. 2013. “Intensity-Response” Effects of Electroacupuncture on Gastric Motility and Its Underlying Peripheral Neural Mechanism. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-479451
Modern Language Association (MLA)
Su, Yang-Shuai…[et al.]. “Intensity-Response” Effects of Electroacupuncture on Gastric Motility and Its Underlying Peripheral Neural Mechanism. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-479451
American Medical Association (AMA)
Su, Yang-Shuai& He, Wei& Wang, Chi& Shi, Hong& Zhao, Yu-Feng& Xin, Juan-Juan…[et al.]. “Intensity-Response” Effects of Electroacupuncture on Gastric Motility and Its Underlying Peripheral Neural Mechanism. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-479451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479451