Reversible Confluent Deep White Matter Abnormalities : A New Variant of Posterior Reversible Encephalopathy Syndrome
Joint Authors
Li, Yuebing
Yacoub, Hussam A.
Castaldo, John
Bemporad, Joshua
Source
Case Reports in Neurological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We describe a confluent deep white matter abnormalities variant of PRES, further strengthening the notion that PRES is a disorder of radiological heterogeneity.
We present 2 cases of PRES with findings of diffuse but reversible vasogenic edema located in the deep periventricular white matter regions of bilateral hemispheres without a clearly posterior distribution.
We feel that this represents a rare variant of PRES on imaging, thus adding to the existing radiological spectrum for this entity.
Both of our patients presented with malignant hypertension (mean arterial blood pressure of 200 mmHg) and developed neurological symptoms that included encephalopathy, seizure, headache, and vision changes.
Additionally, both patients presented with significant subcortical white matter edema that improved dramatically on follow-up imaging.
The clinical and radiological improvement in both patients occurred following successful blood pressure management.
It is possible that the deep white matter changes of PRES are seen exclusively in the setting of severe accelerated hypertension.
Our case reports reveal that, in patients with hypertensive encephalopathy, a deep white matter pattern of diffuse signal changes may not necessarily indicate chronic ischemic changes and follow-up imaging studies are essential to rule out a diagnosis of PRES.
American Psychological Association (APA)
Li, Yuebing& Castaldo, John& Bemporad, Joshua& Yacoub, Hussam A.. 2013. Reversible Confluent Deep White Matter Abnormalities : A New Variant of Posterior Reversible Encephalopathy Syndrome. Case Reports in Neurological Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-479574
Modern Language Association (MLA)
Li, Yuebing…[et al.]. Reversible Confluent Deep White Matter Abnormalities : A New Variant of Posterior Reversible Encephalopathy Syndrome. Case Reports in Neurological Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-479574
American Medical Association (AMA)
Li, Yuebing& Castaldo, John& Bemporad, Joshua& Yacoub, Hussam A.. Reversible Confluent Deep White Matter Abnormalities : A New Variant of Posterior Reversible Encephalopathy Syndrome. Case Reports in Neurological Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-479574
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479574