Role of Obesity in Asthma Control, the Obesity-Asthma Phenotype
Joint Authors
Novosad, Shannon
Khan, Akram
Wolfe, Bruce
Khan, Supriya
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Asthma is a disease with distinct phenotypes that have implications for both prognosis and therapy.
Epidemiologic studies have demonstrated an association between asthma and obesity.
Further studies have shown that obese asthmatics have poor asthma control and more severe asthma.
This obese-asthma group may represent a unique phenotype.
The mechanisms behind poor asthma control in obese subjects remain unclear, but recent research has focused on adipokines and their effects on the airways as well as the role of oxidative stress.
Both surgical and nonsurgical weight loss therapy have shown promising results with improvements in asthma control and decreased asthma severity.
Comorbid conditions such as gastroesophageal reflux disease and obstructive sleep apnea may also have a role in poor asthma control in obese asthmatics.
Further research is needed to define the mechanisms behind this phenotype which will guide the development of targeted therapies.
American Psychological Association (APA)
Novosad, Shannon& Khan, Supriya& Wolfe, Bruce& Khan, Akram. 2013. Role of Obesity in Asthma Control, the Obesity-Asthma Phenotype. Journal of Allergy،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-479729
Modern Language Association (MLA)
Novosad, Shannon…[et al.]. Role of Obesity in Asthma Control, the Obesity-Asthma Phenotype. Journal of Allergy No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-479729
American Medical Association (AMA)
Novosad, Shannon& Khan, Supriya& Wolfe, Bruce& Khan, Akram. Role of Obesity in Asthma Control, the Obesity-Asthma Phenotype. Journal of Allergy. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-479729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479729