The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NCNga Mice
Joint Authors
Kim, Cheol-Su
Lee, Kyu-Jae
Sajo, Ma. Easter Joy V.
Yoon, Yang-Suk
Yun, Young-Uk
Ignacio, Rosa Mistica C.
Kwak, Hyun-Suk
Kim, Soo-Ki
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hydrogen water (HW) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH).
It has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, HW effect on atopic dermatitis (AD), an inflammatory skin disorder, is poorly documented.
In the present study, we examined the immunological effect of drinking HW on Dermatophagoides farinae-induced AD-like skin in NC/Nga mice.
Mice were administered with HW and purified water (PW) for 25 days.
We evaluated the serum concentration of pro-inflammatory (TNF-α), Th1 (IFN-γ, IL-2, and IL-12p70), Th2 (IL-4, IL-5, and IL-10), and cytokine expressed by both subsets (GM-CSF) to assess their possible relationship to the severity of AD.
The serum levels of cytokines such as IL-10, TNF-α, IL-12p70, and GM-CSF of mice administered with HW was significantly reduced as compared to PW group.
The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice.
This is the first note on the drinking effect of HW on AD, clinically implying a promising potential remedy for treatment of AD.
American Psychological Association (APA)
Ignacio, Rosa Mistica C.& Kwak, Hyun-Suk& Yun, Young-Uk& Sajo, Ma. Easter Joy V.& Yoon, Yang-Suk& Kim, Cheol-Su…[et al.]. 2013. The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NCNga Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-479731
Modern Language Association (MLA)
Ignacio, Rosa Mistica C.…[et al.]. The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NCNga Mice. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-479731
American Medical Association (AMA)
Ignacio, Rosa Mistica C.& Kwak, Hyun-Suk& Yun, Young-Uk& Sajo, Ma. Easter Joy V.& Yoon, Yang-Suk& Kim, Cheol-Su…[et al.]. The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NCNga Mice. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-479731
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479731