The S100BRAGE Axis in Alzheimer's Disease
Joint Authors
Sturchler, Emmanuel
Leclerc, Estelle
Vetter, Stefan W.
Source
Cardiovascular Psychiatry and Neurology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-21
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Increasing evidence suggests that the small EF-hand calcium-binding protein S100B plays an important role in Alzheimer's disease.
Among other evidences are the increased levels of both S100B and its receptor, the Receptor for Advanced Glycation Endproducts (RAGEs) in the AD diseased brain.
The regulation of RAGE signaling by S100B is complex and probably involves other ligands including the amyloid beta peptide (Aβ), the Advanced Glycation Endproducts (AGEs), or transtheyretin.
In this paper we discuss the current literature regarding the role of S100B/RAGE activation in Alzheimer's disease.
American Psychological Association (APA)
Leclerc, Estelle& Sturchler, Emmanuel& Vetter, Stefan W.. 2010. The S100BRAGE Axis in Alzheimer's Disease. Cardiovascular Psychiatry and Neurology،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-479816
Modern Language Association (MLA)
Leclerc, Estelle…[et al.]. The S100BRAGE Axis in Alzheimer's Disease. Cardiovascular Psychiatry and Neurology No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-479816
American Medical Association (AMA)
Leclerc, Estelle& Sturchler, Emmanuel& Vetter, Stefan W.. The S100BRAGE Axis in Alzheimer's Disease. Cardiovascular Psychiatry and Neurology. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-479816
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479816