Clinical and Pathological Characteristics of Organized Hematoma
Joint Authors
Watanabe, Tomoo
Izuhara, Kenji
Kubota, Toshinori
Kakehata, Seiji
Ohta, Nobuo
Ishida, Akihiro
Aoyagi, Masaru
Ito, Tsukasa
Matsubara, Atsushi
Suzuki, Yusuke
Source
International Journal of Otolaryngology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To study the clinical and pathological characteristics of patients with organized hematoma with malignant features in maxillary sinuses.
Subjects and Methods.
This was a retrospective study of five patients who were treated surgically for organized hematoma.
The preoperative CT and MRI findings were studied clinically.
The expressions of CD31, CD34, and periostin in surgical samples were investigated by immunohistochemistry.
Results.
The clinical features of organized hematoma, such as a mass expanding from the maxillary sinus with bone destruction, resembled those of maxillary carcinoma.
However, CT and MRI provided sufficient and useful information to differentiate this condition from malignancy.
Surgical resection was the first-line treatment because of the presence of a firm capsule.
Characteristic histopathological findings were a mixture of dilated vessels, hemorrhage, fibrin exudation, fibrosis, hyalinization, and neovascularization.
The expressions of periostin, CD31, and CD34 were observed in organized hematoma of the maxillary sinus.
Conclusion.
The expressions of periostin, CD31, and CD34 were observed in organized hematoma of the maxillary sinus.
Organized hematoma is characterized pathologically by a mixture of bleeding, dilated vessels, hemorrhage, fibrin exudation, fibrosis, hyalinization, and neovascularization.
CT and MRI show heterogeneous findings reflecting a mixture of these pathological entities.
American Psychological Association (APA)
Ohta, Nobuo& Watanabe, Tomoo& Ito, Tsukasa& Kubota, Toshinori& Suzuki, Yusuke& Ishida, Akihiro…[et al.]. 2013. Clinical and Pathological Characteristics of Organized Hematoma. International Journal of Otolaryngology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-479829
Modern Language Association (MLA)
Ohta, Nobuo…[et al.]. Clinical and Pathological Characteristics of Organized Hematoma. International Journal of Otolaryngology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-479829
American Medical Association (AMA)
Ohta, Nobuo& Watanabe, Tomoo& Ito, Tsukasa& Kubota, Toshinori& Suzuki, Yusuke& Ishida, Akihiro…[et al.]. Clinical and Pathological Characteristics of Organized Hematoma. International Journal of Otolaryngology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-479829
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479829