Antibacterial Activity of Murrayaquinone A and 6-Methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione
Joint Authors
Saha, Chandan
Chakraborty, Biswanath
Chakraborty, Suchandra
Source
International Journal of Microbiology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
The antibacterial activity of Murrayaquinone A (10), a naturally occurring carbazoloquinone alkaloid, and 6-methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione (11), a synthetic carbazoloquinone, both obtained during the development of the synthesis of Carbazomycin G, having unique quinone moiety, was studied against Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative (Escherichia coli and Pseudomonas sp.) bacteria.
Compound 10 showed antibacterial activities against both of Escherichia coli and Staphylococcus aureus whereas compound 11 indicated the activity against Staphylococcus aureus only.
Both compounds 10 and 11 exhibited minimum inhibitory concentration (MIC) of 50 μg mL−1 against Staphylococcus aureus.
American Psychological Association (APA)
Chakraborty, Biswanath& Chakraborty, Suchandra& Saha, Chandan. 2014. Antibacterial Activity of Murrayaquinone A and 6-Methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione. International Journal of Microbiology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-479871
Modern Language Association (MLA)
Chakraborty, Biswanath…[et al.]. Antibacterial Activity of Murrayaquinone A and 6-Methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione. International Journal of Microbiology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-479871
American Medical Association (AMA)
Chakraborty, Biswanath& Chakraborty, Suchandra& Saha, Chandan. Antibacterial Activity of Murrayaquinone A and 6-Methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione. International Journal of Microbiology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-479871
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479871