Oral Leukoplakia as It Relates to HPV Infection : A Review
Joint Authors
Source
International Journal of Dentistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Leukoplakia is the most common potentially malignant lesion of the oral cavity and can be categorised according to its clinical appearance as homogeneous or nonhomogenous.
Tobacco and areca nut use, either alone or in combination are the most common risk factors for oral leukoplakia, but some oral leukoplakias are idiopathic.
Some leukoplakias arise within fields of precancerized oral epithelium in which the keratinocytes may be at different stages of cytogenetic transformation.
Leukoplakias may unpredictably regress, may remain stable, or may progress to carcinoma.
There is a greater risk of carcinomatous transformation of idiopathic leukoplakia, of non-homogenous leukoplakia, of leukoplakia affecting the floor of the mouth; the ventrolateral surface of the tongue and the maxillary retromolar and adjoining soft palate (collectively called high-risk sites), of leukoplakia with high-grade epithelial dysplasia, and of leukoplakia in which the keratinocytes carry cytogenetic alterations associated with carcinomatous transformation.
Although there appears to be some link between human papillomavirus (HPV) and oral leukoplakia, there is little evidence to support a causal relationship either between HPV infection and oral leukoplakia or between HPV-infected leukoplakic keratinocytes and their carcinomatous transformation.
American Psychological Association (APA)
Feller, Liviu& Lemmer, J.. 2012. Oral Leukoplakia as It Relates to HPV Infection : A Review. International Journal of Dentistry،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-479903
Modern Language Association (MLA)
Feller, Liviu& Lemmer, J.. Oral Leukoplakia as It Relates to HPV Infection : A Review. International Journal of Dentistry No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-479903
American Medical Association (AMA)
Feller, Liviu& Lemmer, J.. Oral Leukoplakia as It Relates to HPV Infection : A Review. International Journal of Dentistry. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-479903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479903