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Genetic Influences on Physiological and Subjective Responses to an Aerobic Exercise Session among Sedentary Adults
Joint Authors
Bryan, Angela D.
Karoly, Hollis C.
Hutchison, Kent E.
Magnan, Renee E.
Harlaar, Nicole
Stevens, Courtney J.
Source
Journal of Cancer Epidemiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-29
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
To determine whether genetic variants suggested by the literature to be associated with physiology and fitness phenotypes predicted differential physiological and subjective responses to a bout of aerobic exercise among inactive but otherwise healthy adults.
Method.
Participants completed a 30-minute submaximal aerobic exercise session.
Measures of physiological and subjective responding were taken before, during, and after exercise.
14 single nucleotide polymorphisms (SNPs) that have been previously associated with various exercise phenotypes were tested for associations with physiological and subjective response to exercise phenotypes.
Results.
We found that two SNPs in the FTO gene (rs8044769 and rs3751812) were related to positive affect change during exercise.
Two SNPs in the CREB1 gene (rs2253206 and 2360969) were related to change in temperature during exercise and with maximal oxygen capacity (VO2 max).
The SLIT2 SNP rs1379659 and the FAM5C SNP rs1935881 were associated with norepinephrine change during exercise.
Finally, the OPRM1 SNP rs1799971 was related to changes in norepinephrine, lactate, and rate of perceived exertion (RPE) during exercise.
Conclusion.
Genetic factors influence both physiological and subjective responses to exercise.
A better understanding of genetic factors underlying physiological and subjective responses to aerobic exercise has implications for development and potential tailoring of exercise interventions.
American Psychological Association (APA)
Karoly, Hollis C.& Stevens, Courtney J.& Magnan, Renee E.& Harlaar, Nicole& Hutchison, Kent E.& Bryan, Angela D.. 2012. Genetic Influences on Physiological and Subjective Responses to an Aerobic Exercise Session among Sedentary Adults. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-479904
Modern Language Association (MLA)
Karoly, Hollis C.…[et al.]. Genetic Influences on Physiological and Subjective Responses to an Aerobic Exercise Session among Sedentary Adults. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-479904
American Medical Association (AMA)
Karoly, Hollis C.& Stevens, Courtney J.& Magnan, Renee E.& Harlaar, Nicole& Hutchison, Kent E.& Bryan, Angela D.. Genetic Influences on Physiological and Subjective Responses to an Aerobic Exercise Session among Sedentary Adults. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-479904
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479904