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Schistosoma Tegument Proteins in Vaccine and Diagnosis Development : An Update
Joint Authors
Carvalho Alves, Clarice
Fonseca, Cristina Toscano
Braz Figueiredo Carvalho, Gardênia
de Melo, Tatiane Teixeira
Source
Journal of Parasitology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The development of a vaccine against schistosomiasis and also the availability of a more sensitive diagnosis test are important tools to help chemotherapy in controlling disease transmission.
Bioinformatics tools, together with the access to parasite genome, published recently, should help generate new knowledge on parasite biology and search for new vaccines or therapeutic targets and antigens to be used in the disease diagnosis.
Parasite surface proteins, especially those expressed in schistosomula tegument, represent interesting targets to be used in vaccine formulations and in the diagnosis of early infections, since the tegument represents the interface between host and parasite and its molecules are responsible for essential functions to parasite survival.
In this paper we will present the advances in the development of vaccines and diagnosis tests achieved with the use of the information from schistosome genome focused on parasite tegument as a source for antigens.
American Psychological Association (APA)
Fonseca, Cristina Toscano& Braz Figueiredo Carvalho, Gardênia& Carvalho Alves, Clarice& de Melo, Tatiane Teixeira. 2012. Schistosoma Tegument Proteins in Vaccine and Diagnosis Development : An Update. Journal of Parasitology Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-479977
Modern Language Association (MLA)
Fonseca, Cristina Toscano…[et al.]. Schistosoma Tegument Proteins in Vaccine and Diagnosis Development : An Update. Journal of Parasitology Research No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-479977
American Medical Association (AMA)
Fonseca, Cristina Toscano& Braz Figueiredo Carvalho, Gardênia& Carvalho Alves, Clarice& de Melo, Tatiane Teixeira. Schistosoma Tegument Proteins in Vaccine and Diagnosis Development : An Update. Journal of Parasitology Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-479977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479977