![](/images/graphics-bg.png)
Booster Vaccination : The Role of Reduced Antigen Content Vaccines as a Preschool Booster
Joint Authors
Conversano, Michele
Zoppi, Giorgio
Trucchi, Cecilia
Zivelonghi, Giambattista
Gabutti, Giovanni
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-11
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The need for boosters for tetanus, diphtheria, pertussis, and polio, starting from preschool age, is related to the waning immune protection conferred by vaccination, the elimination/reduction of natural boosters due to large-scale immunization programs, and the possibility of reintroduction of wild agents from endemic areas.
Taking into account the relevance of safety/tolerability in the compliance with vaccination among the population, it have been assessed whether today enough scientific evidences are available to support the use of dTap-IPV booster in preschool age.
The review of the literature was conducted using the PubMed search engine.
A total of 41 works has been selected; besides, the documentation produced by the World Health Organization, the European Centre for Disease Control, and the Italian Ministry of Health has been consulted.
Many recent papers confirm the opportunity to use a low antigenic dose vaccine starting from 4 to 6 years of age.
There is also evidence that 10 years after immunization the rate of seroprotected subjects against diphtheria does not differ significantly between those vaccinated with paediatric dose (DTaP) or reduced dose (dTaP or dTap) product.
The dTpa vaccine is highly immunogenic for diphtheria toxoids regardless of prior vaccination history (2 + 1 and 3 + 1 schedules).
American Psychological Association (APA)
Gabutti, Giovanni& Trucchi, Cecilia& Conversano, Michele& Zivelonghi, Giambattista& Zoppi, Giorgio. 2014. Booster Vaccination : The Role of Reduced Antigen Content Vaccines as a Preschool Booster. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-479981
Modern Language Association (MLA)
Gabutti, Giovanni…[et al.]. Booster Vaccination : The Role of Reduced Antigen Content Vaccines as a Preschool Booster. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-479981
American Medical Association (AMA)
Gabutti, Giovanni& Trucchi, Cecilia& Conversano, Michele& Zivelonghi, Giambattista& Zoppi, Giorgio. Booster Vaccination : The Role of Reduced Antigen Content Vaccines as a Preschool Booster. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-479981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-479981