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Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Leishmaniasis has reemerged in recent years showing a wider geographic distribution and increased global incidence of human and canine disease than previously known.
Dogs are the main domestic/peridomestic reservoir hosts of zoonotic visceral leishmaniasis caused by Leishmania infantum.
Since the evolution of leishmaniasis and clinical appearance is a consequence of complex interactions between the parasite and host immune response, a profound knowledge about the immune profile developed in dog's infection is crucial for vaccine and immunomodulatory therapy design.
The main goal of this paper is to compile the recent advances made on cytokine and phenotypic cell profiles in different tissues and organs of dogs infected with L.
infantum.
This paper also stressed that the knowledge of the immune responses developed, namely, in liver, lymph node, and spleen is very limited.
All data emphasizes that more research on canine leishmaniasis is necessary for the development of new and efficacious tools to control zoonotic leishmaniasis.
American Psychological Association (APA)
Maia, Carla& Campino, Lenea. 2011. Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog. Journal of Tropical Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-480006
Modern Language Association (MLA)
Maia, Carla& Campino, Lenea. Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog. Journal of Tropical Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-480006
American Medical Association (AMA)
Maia, Carla& Campino, Lenea. Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog. Journal of Tropical Medicine. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-480006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480006