Neuroleptic Malignant Syndrome in a Patient with Tongue Cancer : A Report of a Rare Case
Joint Authors
Onizawa, Kojiro
Itoh, Hiroyuki
Yamagata, Kenji
Bukawa, Hiroki
Yanagawa, Toru
Tamaoka, Akira
Tomidokoro, Yasushi
Baba, Osamu
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Neuroleptic malignant syndrome (NMS) is a rare but life-threatening complication of neuroleptic drugs, which are used widely in head and neck cancer (HANC) patients who develop delirium.
Methods and Results.
Postoperative delirium in a 39-year-old man with tongue cancer was treated with haloperidol and chlorpromazine.
Three days after the first administration of antipsychotics, the patient exhibited elevated body temperature, autonomic and extrapyramidal symptoms, and impaired consciousness.
A definitive diagnosis was made using the research diagnostic criteria for NMS in the DSM-IV, and the antipsychotics were immediately discontinued.
The patient was given dantrolene and bromocriptine to treat the NMS.
The patient’s hyperthermia, elevated creatinin kinase (CK), and muscle rigidity improved gradually, with all symptoms of NMS resolving completely by 13 days after the diagnosis.
Conclusions.
HANC surgeons must be alert for early signs of NMS and use antipsychotics conservatively to avoid NMS and its potentially fatal outcome.
American Psychological Association (APA)
Baba, Osamu& Yamagata, Kenji& Tomidokoro, Yasushi& Tamaoka, Akira& Itoh, Hiroyuki& Yanagawa, Toru…[et al.]. 2013. Neuroleptic Malignant Syndrome in a Patient with Tongue Cancer : A Report of a Rare Case. Case Reports in Dentistry،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-480080
Modern Language Association (MLA)
Baba, Osamu…[et al.]. Neuroleptic Malignant Syndrome in a Patient with Tongue Cancer : A Report of a Rare Case. Case Reports in Dentistry No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-480080
American Medical Association (AMA)
Baba, Osamu& Yamagata, Kenji& Tomidokoro, Yasushi& Tamaoka, Akira& Itoh, Hiroyuki& Yanagawa, Toru…[et al.]. Neuroleptic Malignant Syndrome in a Patient with Tongue Cancer : A Report of a Rare Case. Case Reports in Dentistry. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-480080
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480080