![](/images/graphics-bg.png)
Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig
Joint Authors
Lafitte, Stéphane
Barandon, Laurent
Caillaud, Dominique
Réant, Patricia
Dos Santos, Pierre
Calderon, Joachim
Roques, Xavier
Couffinhal, Thierry
Source
Cardiology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We present and characterize an original experimental model to create a chronic ischemic heart failure in pig.
Two ameroid constrictors were placed around the LAD and the circumflex artery.
Two months after surgery, pigs presented a poor LV function associated with a severe mitral valve insufficiency.
Echocardiography analysis showed substantial anomalies in radial and circumferential deformations, both on the anterior and lateral surface of the heart.
These anomalies in function were coupled with anomalies of perfusion observed in echocardiography after injection of contrast medium.
No demonstration of myocardial infarction was observed with histological analysis.
Our findings suggest that we were able to create and to stabilize a chronic ischemic heart failure model in the pig.
This model represents a useful tool for the development of new medical or surgical treatment in this field.
American Psychological Association (APA)
Barandon, Laurent& Calderon, Joachim& Réant, Patricia& Caillaud, Dominique& Lafitte, Stéphane& Roques, Xavier…[et al.]. 2010. Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig. Cardiology Research and Practice،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-480103
Modern Language Association (MLA)
Barandon, Laurent…[et al.]. Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig. Cardiology Research and Practice No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-480103
American Medical Association (AMA)
Barandon, Laurent& Calderon, Joachim& Réant, Patricia& Caillaud, Dominique& Lafitte, Stéphane& Roques, Xavier…[et al.]. Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig. Cardiology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-480103
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480103