Tandemly Arrayed Genes in Vertebrate Genomes
Joint Authors
Source
Comparative and Functional Genomics
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-09-21
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Tandemly arrayed genes (TAGs) are duplicated genes that are linked as neighbors on a chromosome, many of which have important physiological and biochemical functions.
Here we performed a survey of these genes in 11 available vertebrate genomes.
TAGs account for an average of about 14% of all genes in these vertebrate genomes, and about 25% of all duplications.
The majority of TAGs (72–94%) have parallel transcription orientation (i.e., they are encoded on the same strand) in contrast to the genome, which has about 50% of its genes in parallel transcription orientation.
The majority of tandem arrays have only two members.
In all species, the proportion of genes that belong to TAGs tends to be higher in large gene families than in small ones; together with our recent finding that tandem duplication played a more important role than retroposition in large families, this fact suggests that among all types of duplication mechanisms, tandem duplication is the predominant mechanism of duplication, especially in large families.
Finally, several species have a higher proportion of large tandem arrays that are species-specific than random expectation.
American Psychological Association (APA)
Pan, Deng& Zhang, Liqing. 2008. Tandemly Arrayed Genes in Vertebrate Genomes. Comparative and Functional Genomics،Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-480279
Modern Language Association (MLA)
Pan, Deng& Zhang, Liqing. Tandemly Arrayed Genes in Vertebrate Genomes. Comparative and Functional Genomics No. 2008 (2008), pp.1-11.
https://search.emarefa.net/detail/BIM-480279
American Medical Association (AMA)
Pan, Deng& Zhang, Liqing. Tandemly Arrayed Genes in Vertebrate Genomes. Comparative and Functional Genomics. 2008. Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-480279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480279