The Role of Placental Homeobox Genes in Human Fetal Growth Restriction
Joint Authors
Brennecke, Shaun Patrick
Rajaraman, Gayathri
Kalionis, Bill
Murthi, Padma
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant perinatal and paediatric morbidity and mortality, and an increased risk of chronic disease later in adult life.
One of the key causes of adverse pregnancy outcome is fetal growth restriction (FGR).
While a number of maternal, fetal, and environmental factors are known causes of FGR, the majority of FGR cases remain idiopathic.
These idiopathic FGR pregnancies are frequently associated with placental insufficiency, possibly as a result of placental maldevelopment.
Understanding the molecular mechanisms of abnormal placental development in idiopathic FGR is, therefore, of increasing importance.
Here, we review our understanding of transcriptional control of normal placental development and abnormal placental development associated with human idiopathic FGR.
We also assess the potential for understanding transcriptional control as a means for revealing new molecular targets for the detection, diagnosis, and clinical management of idiopathic FGR.
American Psychological Association (APA)
Murthi, Padma& Rajaraman, Gayathri& Brennecke, Shaun Patrick& Kalionis, Bill. 2011. The Role of Placental Homeobox Genes in Human Fetal Growth Restriction. Journal of Pregnancy،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-480527
Modern Language Association (MLA)
Murthi, Padma…[et al.]. The Role of Placental Homeobox Genes in Human Fetal Growth Restriction. Journal of Pregnancy No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-480527
American Medical Association (AMA)
Murthi, Padma& Rajaraman, Gayathri& Brennecke, Shaun Patrick& Kalionis, Bill. The Role of Placental Homeobox Genes in Human Fetal Growth Restriction. Journal of Pregnancy. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-480527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480527