Ghrelin and Functional Dyspepsia
Joint Authors
Iwakura, Hiroshi
Ariyasu, Hiroyuki
Kangawa, Kenji
Akamizu, Takashi
Source
International Journal of Peptides
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD).
While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function.
Communication between the brain and gut occurs via direct neural connections or endocrine signaling events.
Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it may play a pathophysiological role in FD.
It is also possible that the functional abnormalities in FD may affect ghrelin production in the stomach.
Plasma ghrelin levels are reported to be altered in FD, correlating with FD symptom score.
Furthermore, some patients with FD suffer from anorexia with body-weight loss.
As ghrelin increases gastric emptying and promotes feeding, ghrelin therapy may be a new approach to the treatment of FD.
American Psychological Association (APA)
Akamizu, Takashi& Iwakura, Hiroshi& Ariyasu, Hiroyuki& Kangawa, Kenji. 2010. Ghrelin and Functional Dyspepsia. International Journal of Peptides،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-480560
Modern Language Association (MLA)
Akamizu, Takashi…[et al.]. Ghrelin and Functional Dyspepsia. International Journal of Peptides No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-480560
American Medical Association (AMA)
Akamizu, Takashi& Iwakura, Hiroshi& Ariyasu, Hiroyuki& Kangawa, Kenji. Ghrelin and Functional Dyspepsia. International Journal of Peptides. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-480560
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480560