Progressive Multifocal Leukoencephalopathy in a 62-Year-Old Immunocompetent Woman
Joint Authors
Bordea, Doru
Kumar, Yogesh
Sena, Kanaga N.
Gourineni, Venkata C.
Juvet, Tristan
Source
Case Reports in Neurological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Progressive multifocal encephalopathy (PML) is a rare demyelinating disease that typically presents in immunodeficient patients.
We report a case of a previously healthy 62-Year-Old woman who suffered from an unsteady gait, throbbing headaches, and progressive left-sided weakness and numbness.
Stroke was initially suspected based on imaging and symptoms.
A series of follow-up magnetic resonance images of the brain showed a right parietal lesion growing in size as the patient became unable to walk and experienced increasing lethargy and confusion.
A biopsy of the lesion was positive for the John Cunningham virus (JCV).
A diagnosis of PML was made and she was started on mefloquine.
No improvement was seen on this treatment and her condition worsened.
Although PML remains uncommon in immunocompetent individuals, it cannot be ruled out based on their immune status.
Although the exact cause remains uncertain, underlying or transient states of immunosuppression may be responsible for reactivation of the JCV in these patients.
American Psychological Association (APA)
Gourineni, Venkata C.& Juvet, Tristan& Kumar, Yogesh& Bordea, Doru& Sena, Kanaga N.. 2014. Progressive Multifocal Leukoencephalopathy in a 62-Year-Old Immunocompetent Woman. Case Reports in Neurological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-480651
Modern Language Association (MLA)
Gourineni, Venkata C.…[et al.]. Progressive Multifocal Leukoencephalopathy in a 62-Year-Old Immunocompetent Woman. Case Reports in Neurological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-480651
American Medical Association (AMA)
Gourineni, Venkata C.& Juvet, Tristan& Kumar, Yogesh& Bordea, Doru& Sena, Kanaga N.. Progressive Multifocal Leukoencephalopathy in a 62-Year-Old Immunocompetent Woman. Case Reports in Neurological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-480651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480651