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Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated Pathogens
Joint Authors
Coudeyras, Sophie
Vermerie, Marion
Forestier, Christiane
Jugie, Gwendoline
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-01-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
The ability of a probiotic Lactobacillus rhamnosus strain (Lcr35) to adhere to cervical and vaginal cells and to affect the viability of two main vaginosis-associated pathogens, Prevotella bivia, Gardnerella vaginalis, as well as Candida albicans was investigated.
Methods.
Adhesion ability was determined in vitro with immortalized epithelial cells from the endocervix, ectocervix, and vagina.
Coculture experiments were performed to count viable pathogens cells in the presence of Lcr35.
Results.
Lcr35 was able to specifically and rapidly adhere to the three cell lines.
In coculture assays, a decrease in pathogen cell division rate was observed as from 4 hours of incubation and bactericidal activity after a longer period of incubation, mostly with P.
bivia.
Conclusion.
The ability of Lcr35 to adhere to cervicovaginal cells and its antagonist activities against vaginosis-associated pathogens suggest that this probiotic strain is a promising candidate for use in therapy.
American Psychological Association (APA)
Coudeyras, Sophie& Jugie, Gwendoline& Vermerie, Marion& Forestier, Christiane. 2009. Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated Pathogens. Infectious Diseases in Obstetrics and Gynecology،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-480689
Modern Language Association (MLA)
Coudeyras, Sophie…[et al.]. Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated Pathogens. Infectious Diseases in Obstetrics and Gynecology No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-480689
American Medical Association (AMA)
Coudeyras, Sophie& Jugie, Gwendoline& Vermerie, Marion& Forestier, Christiane. Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated Pathogens. Infectious Diseases in Obstetrics and Gynecology. 2009. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-480689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480689