Biologicals and Fetal Cell Therapy for Wound and Scar Management
Joint Authors
Ramelet, Albert-Adrien
Scaletta, Corinne
Pioletti, Dominique
Raffoul, Wassim
Laurent-Applegate, L. A.
Hirt-Burri, Nathalie
de Buys Roessingh, Anthony
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-18
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Few biopharmaceutical preparations developed from biologicals are available for tissue regeneration and scar management.
When developing biological treatments with cellular therapy, selection of cell types and establishment of consistent cell banks are crucial steps in whole-cell bioprocessing.
Various cell types have been used in treatment of wounds to reduce scar to date including autolog and allogenic skin cells, platelets, placenta, and amniotic extracts.
Experience with fetal cells show that they may provide an interesting cell choice due to facility of outscaling and known properties for wound healing without scar.
Differential gene profiling has helped to point to potential indicators of repair which include cell adhesion, extracellular matrix, cytokines, growth factors, and development.
Safety has been evidenced in Phase I and II clinical fetal cell use for burn and wound treatments with different cell delivery systems.
We present herein that fetal cells present technical and therapeutic advantages compared to other cell types for effective cell-based therapy for wound and scar management.
American Psychological Association (APA)
Hirt-Burri, Nathalie& Ramelet, Albert-Adrien& Raffoul, Wassim& de Buys Roessingh, Anthony& Scaletta, Corinne& Pioletti, Dominique…[et al.]. 2011. Biologicals and Fetal Cell Therapy for Wound and Scar Management. ISRN Dermatology،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-480724
Modern Language Association (MLA)
Hirt-Burri, Nathalie…[et al.]. Biologicals and Fetal Cell Therapy for Wound and Scar Management. ISRN Dermatology No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-480724
American Medical Association (AMA)
Hirt-Burri, Nathalie& Ramelet, Albert-Adrien& Raffoul, Wassim& de Buys Roessingh, Anthony& Scaletta, Corinne& Pioletti, Dominique…[et al.]. Biologicals and Fetal Cell Therapy for Wound and Scar Management. ISRN Dermatology. 2011. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-480724
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480724