![](/images/graphics-bg.png)
Oxytocin and Psychological Factors Affecting Type 2 Diabetes Mellitus
Joint Authors
Raptis, A. E.
Papageorgiou, C. C.
Tsiotra, P. C.
Papadimitriou, George N.
Raptis, S. A.
Dimitriadis, George
Kontoangelos, Konstantinos A.
Rabavilas, A. D.
Source
Experimental Diabetes Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The aim of this study was to investigate the association of oxytocin with trait and state psychological factors in type 2 diabetic patients.
Methods.
OXT and psychological variables were analyzed from 86 controlled diabetic patients (glycosylated haemoglobin A1c (HbA1c) < 7%) from 45 uncontrolled diabetic patients (HbA1c ≥ 7).
Psychological characteristics were assessed with the Eysenck Personality Questionnaire (EPQ), while state psychological characteristics were measured with the Symptom Checklist 90-R (SCL 90-R).
Blood samples were taken for measuring oxytocin in both subgroups during the initial phase of the study.
One year later, the uncontrolled diabetic patients were reevaluated with the use of the same psychometric instruments.
Results.
During the first evaluation of the uncontrolled diabetic patients, a statistically significant positive relationship between the levels of OXT and psychoticism in EPQ rating scale (P<0.013) was observed.
For controlled diabetic patients, a statistically significant negative relationship between oxytocin and somatization (P<0.030), as well as obsessive-compulsive scores (P<0.047) in SCL-90 rating scale, was observed.
During the second assessment, the values of OXT decreased when the patients managed to control their metabolic profile.
Conclusions.
The OXT is in association with psychoticism, somatization, and obsessionality may be implicated in T2DM.
American Psychological Association (APA)
Kontoangelos, Konstantinos A.& Raptis, A. E.& Papageorgiou, C. C.& Tsiotra, P. C.& Papadimitriou, George N.& Rabavilas, A. D.…[et al.]. 2012. Oxytocin and Psychological Factors Affecting Type 2 Diabetes Mellitus. Experimental Diabetes Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-480820
Modern Language Association (MLA)
Kontoangelos, Konstantinos A.…[et al.]. Oxytocin and Psychological Factors Affecting Type 2 Diabetes Mellitus. Experimental Diabetes Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-480820
American Medical Association (AMA)
Kontoangelos, Konstantinos A.& Raptis, A. E.& Papageorgiou, C. C.& Tsiotra, P. C.& Papadimitriou, George N.& Rabavilas, A. D.…[et al.]. Oxytocin and Psychological Factors Affecting Type 2 Diabetes Mellitus. Experimental Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-480820
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480820