Autoimmune Hepatitis Triggered by Anti-TNF-α Therapy
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-08
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Autoimmune hepatitis (AIH) is occasionally triggered by drug treatments.
Recently, as biological agents are becoming widely used for autoimmune disorders, there have been a growing number of reports of the development of autoimmune processes related to these agents.
A 52-year-old Japanese woman with psoriasis developed liver damage two months after initiation of anti-TNF-α therapy with adalimumab.
Liver histological findings were compatible with AIH, and positive conversions of ANAs were detected.
The patient was treated with prednisolone and had a good response.
While some cases of AIH triggered by anti-TNF-α therapies have been reported, the pathogenesis remains unspecified.
When elevation of liver enzymes is observed with high IgG levels and seropositivity of ANA during the course of anti-TNF-α therapy, liver biopsy findings may be essential and important to make definitive diagnosis of AIH.
American Psychological Association (APA)
Nakayama, Satoshi. 2013. Autoimmune Hepatitis Triggered by Anti-TNF-α Therapy. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-480893
Modern Language Association (MLA)
Nakayama, Satoshi. Autoimmune Hepatitis Triggered by Anti-TNF-α Therapy. Case Reports in Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-480893
American Medical Association (AMA)
Nakayama, Satoshi. Autoimmune Hepatitis Triggered by Anti-TNF-α Therapy. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-480893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480893