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Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review
Joint Authors
Liu, Wei
Li, Yange
Li, Huixia
Bao, Fengchang
Tan, Hongna
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-04
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We present a rare case of cryptococcal lymphadenitis without immunocompromization in a two-and-a-half-year-old child.
He was referred to our center with a fifteen-day history of continued fever.
Ultrasound and computed tomography (CT) revealed the enlargement of multiple lymph nodes and lung reticulonodular shadows.
Hematological, immunological, and microbiological tests for hepatitis, lymphoma, AIDS, and immunoglobulin deficiencies were negative.
Laboratory tests demonstrated elevated erythrocyte sedimentation rate, elevated plasma and urinary ß2-microglobulin (ß2-MG) levels, and elevated C-reactive protein and fibrinogen.
Both blood routine and bone marrow aspiration showed elevated eosinophil granulocytes.
The diagnosis of cryptococcal lymphadenitis was obtained by excisional biopsy of the cervical lymph nodes.
The patient was treated with intravenous amphotericin B and oral flucytosine for five weeks, then with subsequent oral fluconazole for three months.
The patient is now doing well.
Our case suggests that the diagnosis of cryptococcal lymphadenitis is very difficult without etiology and pathology, especially for a patient with a normal immune system; lymph node biopsy is necessary to diagnose it, and immediate antifungal treatment is necessary to treat it.
American Psychological Association (APA)
Bao, Fengchang& Tan, Hongna& Liu, Wei& Li, Yange& Li, Huixia. 2013. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-481014
Modern Language Association (MLA)
Bao, Fengchang…[et al.]. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-481014
American Medical Association (AMA)
Bao, Fengchang& Tan, Hongna& Liu, Wei& Li, Yange& Li, Huixia. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-481014
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481014