Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review

Joint Authors

Liu, Wei
Li, Yange
Li, Huixia
Bao, Fengchang
Tan, Hongna

Source

Case Reports in Pediatrics

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-06-04

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Medicine

Abstract EN

We present a rare case of cryptococcal lymphadenitis without immunocompromization in a two-and-a-half-year-old child.

He was referred to our center with a fifteen-day history of continued fever.

Ultrasound and computed tomography (CT) revealed the enlargement of multiple lymph nodes and lung reticulonodular shadows.

Hematological, immunological, and microbiological tests for hepatitis, lymphoma, AIDS, and immunoglobulin deficiencies were negative.

Laboratory tests demonstrated elevated erythrocyte sedimentation rate, elevated plasma and urinary ß2-microglobulin (ß2-MG) levels, and elevated C-reactive protein and fibrinogen.

Both blood routine and bone marrow aspiration showed elevated eosinophil granulocytes.

The diagnosis of cryptococcal lymphadenitis was obtained by excisional biopsy of the cervical lymph nodes.

The patient was treated with intravenous amphotericin B and oral flucytosine for five weeks, then with subsequent oral fluconazole for three months.

The patient is now doing well.

Our case suggests that the diagnosis of cryptococcal lymphadenitis is very difficult without etiology and pathology, especially for a patient with a normal immune system; lymph node biopsy is necessary to diagnose it, and immediate antifungal treatment is necessary to treat it.

American Psychological Association (APA)

Bao, Fengchang& Tan, Hongna& Liu, Wei& Li, Yange& Li, Huixia. 2013. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-481014

Modern Language Association (MLA)

Bao, Fengchang…[et al.]. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-481014

American Medical Association (AMA)

Bao, Fengchang& Tan, Hongna& Liu, Wei& Li, Yange& Li, Huixia. Pediatric Cryptococcal Lymphadenitis in the Absence of AIDS : Case Report and Literature Review. Case Reports in Pediatrics. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-481014

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-481014