Antioxidant, Antimicrobial, and Free Radical Scavenging Potential of Aerial Parts of Periploca aphylla and Ricinus communis
Joint Authors
Iqbal, Jamshed
Khan, Afsar
Bibi, Irum
Farooq, Umar
Zaib, Sumera
Suleman, Saba
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Context.
Many diseases are associated with oxidative stress caused by free radicals.
Objective.
The present study evaluated the in vitro antioxidant and antibacterial activities of various extracts of aerial parts of Periploca aphylla and Ricinus communis.
Materials and Methods.
In vitro antioxidant activities of the plant extract were determined by DPPH and NO scavenging method.
Superoxide anion radical activity was measured by the reduction of nitro blue tetrazolium as compared with standard antioxidants.
Total phenolic contents and antibacterial activities of these plants were determined by gallic acid equivalent (GAE) and serial tube dilution method, respectively.
Results.
Plants showed significant radical scavenging activity.
The results were expressed as IC50.
n-Propyl gallate and 3-t-butyl-4-hydroxyanisole were used as standards for antioxidant assay.
All the extracts of both plants showed comparable IC50 to those of standards.
Plants extract exhibited high phenolic contents and antibacterial activities were comparable with standard drug, Ciprofloxacin.
Discussion and Conclusion.
The present study provides evidence that Periploca aphylla and Ricinus communis prove to be potent natural antioxidants and could replace synthetic antioxidants.
Plants can also be used against pathogenic bacterial strains.
American Psychological Association (APA)
Iqbal, Jamshed& Zaib, Sumera& Farooq, Umar& Khan, Afsar& Bibi, Irum& Suleman, Saba. 2012. Antioxidant, Antimicrobial, and Free Radical Scavenging Potential of Aerial Parts of Periploca aphylla and Ricinus communis. ISRN Pharmacology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481038
Modern Language Association (MLA)
Iqbal, Jamshed…[et al.]. Antioxidant, Antimicrobial, and Free Radical Scavenging Potential of Aerial Parts of Periploca aphylla and Ricinus communis. ISRN Pharmacology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-481038
American Medical Association (AMA)
Iqbal, Jamshed& Zaib, Sumera& Farooq, Umar& Khan, Afsar& Bibi, Irum& Suleman, Saba. Antioxidant, Antimicrobial, and Free Radical Scavenging Potential of Aerial Parts of Periploca aphylla and Ricinus communis. ISRN Pharmacology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-481038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481038