Huntington's Disease : An Immune Perspective
Joint Authors
Kishore, Uday
Verma, Sunil K.
Nayak, Annapurna
Bonifati, Domenico Marco
Ansar, Rafia
Source
Neurology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide repeats.
Neuroinflammation is a typical feature of most neurodegenerative diseases that leads to an array of pathological changes within the affected areas in the brain.
The neurodegeneration in HD is also caused by aberrant immune response in the presence of aggregated mutant huntingtin protein.
The effects of immune activation in HD nervous system are a relatively unexplored area of research.
This paper summarises immunological features associated with development and progression of HD.
American Psychological Association (APA)
Nayak, Annapurna& Ansar, Rafia& Verma, Sunil K.& Bonifati, Domenico Marco& Kishore, Uday. 2011. Huntington's Disease : An Immune Perspective. Neurology Research International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-481077
Modern Language Association (MLA)
Nayak, Annapurna…[et al.]. Huntington's Disease : An Immune Perspective. Neurology Research International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-481077
American Medical Association (AMA)
Nayak, Annapurna& Ansar, Rafia& Verma, Sunil K.& Bonifati, Domenico Marco& Kishore, Uday. Huntington's Disease : An Immune Perspective. Neurology Research International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-481077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481077
