Epigenetic Regulation of B Lymphocyte Differentiation, Transdifferentiation, and Reprogramming
Joint Authors
Roman-Gonzalez, Lidia
Parra, Maribel
Collazo, Olga
Barneda-Zahonero, Bruna
Mahmoudi, Tokameh
Source
Comparative and Functional Genomics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
B cell development is a multistep process that is tightly regulated at the transcriptional level.
In recent years, investigators have shed light on the transcription factor networks involved in all the differentiation steps comprising B lymphopoiesis.
The interplay between transcription factors and the epigenetic machinery involved in establishing the correct genomic landscape characteristic of each cellular state is beginning to be dissected.
The participation of “epigenetic regulator-transcription factor” complexes is also crucial for directing cells during reprogramming into pluripotency or lineage conversion.
In this context, greater knowledge of epigenetic regulation during B cell development, transdifferentiation, and reprogramming will enable us to understand better how epigenetics can control cell lineage commitment and identity.
Herein, we review the current knowledge about the epigenetic events that contribute to B cell development and reprogramming.
American Psychological Association (APA)
Barneda-Zahonero, Bruna& Roman-Gonzalez, Lidia& Collazo, Olga& Mahmoudi, Tokameh& Parra, Maribel. 2012. Epigenetic Regulation of B Lymphocyte Differentiation, Transdifferentiation, and Reprogramming. Comparative and Functional Genomics،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-481132
Modern Language Association (MLA)
Barneda-Zahonero, Bruna…[et al.]. Epigenetic Regulation of B Lymphocyte Differentiation, Transdifferentiation, and Reprogramming. Comparative and Functional Genomics No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-481132
American Medical Association (AMA)
Barneda-Zahonero, Bruna& Roman-Gonzalez, Lidia& Collazo, Olga& Mahmoudi, Tokameh& Parra, Maribel. Epigenetic Regulation of B Lymphocyte Differentiation, Transdifferentiation, and Reprogramming. Comparative and Functional Genomics. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-481132
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481132