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Chloroformic and Methanolic Extracts of Olea europaea L. Leaves Present Anti-Inflammatory and Analgesic Activities
Joint Authors
Chebbi Mahjoub, R
Khemiss, M.
Khemiss, F.
Bouraoui, A.
Dhidah, M.
Dellaï, A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Olea europaea L.
is used in traditional medicine in the Mediterranean areas.
Its natural products are used in the treatment of different disorders, like fighting fever and some infectious diseases such as malaria, the treatment of arrhythmia, and relief of intestinal spasms.
The aim of the current study is to investigate the possible anti-inflammatory and anatinociceptive effects of methanol and chloroformic extracts prepared from leaves of Olea europaea L.
The anti-inflammatory and antinociceptive effects of the different extracts of Olea europaea leaves were assessed after intraperitoneal administration into rats and mice, using the carrageenan-induced paw edema model in rats to test the anti-inflammatory effect and the acetic acid-induced writhing in mice to test the analgesic effect.
The chloroformic and methanolic leaves extracts, studied at the doses of 50, 100, and 200 mg/kg (Body Weight: BW), exhibited significant dose-dependent anti-inflammatory and analgesic activities.
Based on the results obtained, it can be concluded that Olea europaea leaves extracts have anti-inflammatory and antinociceptive effects.
American Psychological Association (APA)
Chebbi Mahjoub, R& Khemiss, M.& Dhidah, M.& Dellaï, A.& Bouraoui, A.& Khemiss, F.. 2011. Chloroformic and Methanolic Extracts of Olea europaea L. Leaves Present Anti-Inflammatory and Analgesic Activities. ISRN Pharmacology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-481192
Modern Language Association (MLA)
Chebbi Mahjoub, R…[et al.]. Chloroformic and Methanolic Extracts of Olea europaea L. Leaves Present Anti-Inflammatory and Analgesic Activities. ISRN Pharmacology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-481192
American Medical Association (AMA)
Chebbi Mahjoub, R& Khemiss, M.& Dhidah, M.& Dellaï, A.& Bouraoui, A.& Khemiss, F.. Chloroformic and Methanolic Extracts of Olea europaea L. Leaves Present Anti-Inflammatory and Analgesic Activities. ISRN Pharmacology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-481192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-481192